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Group B: Lower score risk mortality group; Group A1: number of organ failures >1.
Three hundred and eighty-six patients were included, being 30 (7.8%) in Group 1 (short-term mortality group, median time from organ dysfunction to death: 2.39 (1.75 to 3.25) days) and 356 (92.2%) in Group 2. No difference was found between the groups regarding gender (P = 0.14), age (P = 0.80), being in a public hospital (P = 0.94) or duration of organ dysfunction (P = 0.79).
Respiratory infection was more frequently observed in 1-month mortality group.
Sixteen patients (40%) were classified as NYHA III IV in our study and five out of them were in mortality group.
Among all parameters, Area5, Area6 20, and LF were significantly lower (p = 0.027, p = 0.021, and p = 0.004 respectively) in the mortality group.
The MTHFR 677TT genotype was not significantly associated to an increased mortality, while we observed a non significant trend toward the contrary: for example, the prevalence of TT genotype was only 6.3% in the total mortality group, 8.3% in the group died for cardiovascular causes, as compared to 17.5% in survivors (P = NS).
Group A: Higher score risk mortality group.
The WGCNA* moderate mortality group did not validate.
fThe mortality numbers are cumulative (that is, the 1-year mortality group includes the 30-day mortality group.
There were four cases (10.5%) in the 28-day mortality group, and six cases (15.8%) in the 90-day mortality group.
The mean uNGAL levels were significantly higher in the mortality group.
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