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To investigate differences in sepsis mortality between prepubertal and postpubertal males and females.
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Results: There was no difference in 7-month change in bone parameters between prepubertal I and C groups.
We therefore aimed at analyzing the association between prepubertal BMI at 7 years and pubertal timing at the individual level in this large cohort to determine if there was any association between the degree of prepubertal overweight/obesity and age at sexual maturation, and if age at sexual maturation declined irrespectively of the degree of overweight/obesity.
The purpose of this study was to analyze the association between prepubertal body mass index (BMI) and pubertal timing, as assessed by age at onset of pubertal growth spurt (OGS) and at peak height velocity (PHV), and the secular trend of pubertal timing given the prepubertal BMI.
A significant positive correlation was found between prepubertal ∆IGFs and both prepubertal and total gain in heightSDS.
There also exist distinct differences in sex hormones between prepubertal boys and girls.
Lifetime HbA1c values did not differ between prepubertal and pubertal patients in the whole sample or in the patients without DR or with mild DR (Table 3).
This discrepancy could be attributed to physiological differences between prepubertal and adult females and/or to differences in the ovarian stimulation treatments.
Demonstration of an association between prepubertal insulin resistance and adult CVD risk will allow us to highlight the importance of this phase in the life course evolution of CVD risk.
Our growth assessments did not show any difference of short stature prevalence between prepubertal and pubertal patients, in contrast to the results of Pignatti et al who claimed growth abnormalities to be more prevalent in pubertal patients [ 26].
Excess body weight, equally distributed between prepubertal and pubertal groups, seems an unlikely confounding factor, whereas we cannot exclude that hypertension may be one of these factors since all three case subjects with hypertension belonged to the pubertal group.
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