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Bare nano-Al2O3 particles exhibited partial mortality at concentrations of greater than 200 mg/L.
To summarize, different MWCNT induced D. magna mortality at concentrations above 20 mg/L for 48 h exposure and around 2 mg/L after 96 h exposure.
As-produced CB induces significant mortality at concentrations of 100 mg/L and above.
When embryos were exposed to the compounds from 1 to 48 hpf, we found lethal effects of vinblastine at concentrations >1 μM and 100% mortality at concentrations ≥5 μM; of vincristine at concentrations ≥10 μM; and of phenanthrene at concentrations >1 μM and 100% mortality at concentrations ≥20 μM.
The gold salt used in nanoparticle synthesis (PPh3AuCl) and all of the individual ligands were also tested and had no effect on malformations or mortality at concentrations up to 250 ppm.
This study, which included men and women, enabled the examination of the dose-response relation with total mortality at concentrations >90 and >120 nmol/L although with only a small proportion of the population with concentrations >120 nmol/L (n = 152; 1%) and >150 nmol (n = 21; 0.1%); we did not have power to assess potential adverse outcomes above concentrations of 150 nmol/L.
Similar(54)
Reports suggest frank toxicity with hyper-calcemia at serum concentrations of greater than 200 ng/mL; however, long-term studies of all-cause mortality suggest that vitamin D may show a reverse J-shaped curve in which mortality increases at concentrations of greater than 30 to 48 ng/mL [ 6].
A dose dependent change in median survival time of permethrin-sensitive mites was observed when mites were exposed to nutmeg oil, with a very low mortality observed at concentrations below 6.25%.
For mortality, lowest risks were in subjects with concentrations >90 nmol/L, and there was no evidence of increased mortality at high concentrations, suggesting that a moderate increase in population mean concentrations may have potential health benefit, but <1% of the population had concentrations >120 nmol/L.
This is attributed to greater mortality at increasing concentrations and exposure times.
Apart from the MMS exposure to sea stars (which showed 100% mortality at higher concentrations after 5 d exposure), clear dose response relationships were observed for both genotoxicity endpoints in each species.
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