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Earlier studies indicate an increased risk of osteoporosis and morphometric VFs in AS.
Therefore, the actual incidence of morphometric VFs in AS remains unclear.
The age-specific specific standardized prevalence ratio of morphometric VFs in AS was 3.3 (95% CI 2.1 4.5).
Here, we report the effects of TNF inhibitors on the incidence of morphometric VFs in AS patients.
This is a first study to evaluate the incidence of morphometric VFs in AS patients and to identify the risk factors associated with new VFs.
Table 4 shows the age-specific SPR for morphometric VFs in AS patients compared with the morphometric VFs expected in the Korean general population [ 16].
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We applied the age-specific prevalence of morphometric VF in the Korean general population study to the age distribution of our AS cohort, and calculated an age-standardized prevalence ratio (SPR) and its 95% CI.
Because post-fracture wedging of the vertebrae can contribute to hyperkyphosis and neurologic complications [ 12], it is important to identify the predictors of morphometric VFs if we are to effectively manage AS patients.
The incidence of morphometric VFs increased in AS.
The objectives of this study were to examine the incidence of morphometric VFs on x-ray evaluation in AS patients and to identify the risk factors associated with new VFs.
There was a significant increase in the risk of morphometric VFs among AS patients aged over 40 years (standardized Prevalence rate (SPR) = 3.3, 95% CI = 2.06 to 4.54).
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