Sentence examples for morphology with nuclear from inspiring English sources

HAMLET-treated tumor cells displayed typical apoptotic morphology with nuclear fragmentation and chromatin condensation (Fig. 3A).

However, prefibrotic CIMF is characterized by marked hypercellularity, left-shifted increased granulopoiesis, and a particular megakaryocyte morphology with nuclear features, whereas ET shows hyperlobulated and mature-appearing megakaryocytes [ 10, 21].

In TUNEL assay, CaP-RR cells treated by dual inhibitors (BEZ235 or PI103) combined with RT displayed characteristic apoptotic morphology with nuclear chromatin condensation and fragmentation, whereas those treated by single inhibitors (BKM120 or Rapamycin) combined with RT showed less apoptotic cells and almost no apoptotic cells were found in CaP-RR cells exposed to 6 Gy RT alone.

A problem of this particular study is that the morphology of cells with nuclear EBER signal within the lesions was not always typical for B cells, particularly in stroke lesions and double staining for EBER expression in B cells has not been performed.

As shown in Figure 4, cells exposed to topotecan gemcitabine combination presented typical apoptotic morphology with cell shrinkage, nuclear condensation and fragmentation, and rupture of cells into debris.

Bladder cancer T24 and J82 cells exposed to pemetrexed, gemcitabine and their combinations presented typical apoptotic morphology with cell shrinkage, nuclear condensation and fragmentation, and rupture of cells into debris.

Similar results were observed with fluorescence microscopy showing that PDAC cells exposed to the NHI compounds, gemcitabine and their combination presented the typical apoptotic morphology with cell shrinkage, nuclear condensation and fragmentation, and rupture of cells into debris (inset in Figure 4F).

Cell and nucleus morphology were also considered, with nuclear deformation linked to cell signaling.

The number of cells with nuclear morphology indicative of an apoptotic or mitotic catastrophe phenotype was quantified using a fluorescent microscope (ZEISS Axioplan 2 imaging microscope, ZEISS, Thornwood, NY, USA).

The number of cells with nuclear apoptotic morphology was counted in five fields of 100 cells.

Statistical significance for a change in percentage cells with nuclear apoptotic morphology was determined by two-tailed paired t-tests (assuming equal variance) between the drug combination counts and the single agents.