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While our data exclude a role for total JNK activity on WS cell proliferation or morphology, they do suggest a possible role for MK2.
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Whilst these generic organ models do not reflect the range of MRT patient morphologies, they do allow dose calculations to be adapted to consider individual organ masses and patient age and sex.
The Atlantic species more closely resemble each other in morphology than they do the ocellated electric ray, though as a whole all four Diplobatis species are extremely similar.
Although the lesions that form in PyMT mice treated with the Src inhibitor and those from PyMT/S14−/− mice appear similar in morphology, they likely do not have the same molecular characteristics with regards to cellular differentiation.
4T07 tumor cells with reduced APC levels were significantly less motile and had a more rounded morphology; yet, they did not differ significantly in proliferation or β-catenin/TCF transcriptional activity.
The cells, once seeded in the scaffolds, can adopt a variety of morphologies, demonstrating that they do not need to be part of a tightly packed tissue to form complex shapes.
This is further supported by the fact that although males and females accumulate variance in mandible morphology at different evolutionary rates, they do so along the same shape change trajectories in both common and global morphospace (see Additional file 1).
They do not reproduce cellular morphology, tissue architecture, inter-patients and intratumor heterogeneity.
That study did not include any samples without neurologic disease, and therefore underestimated the heterogeneity in microglia morphology; for example, they did not describe rod-shaped microglia.
Are the assumptions provided here enough to explain the colony morphology also or do they need additional explanations?
They display normal morphology and do not contain any vacuoles.
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