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Our data suggest this previously unrecognised morphology represents the initial stage of an abnormal FDC maturation cycle.
These data imply that this novel, abnormal mature FDC morphology represents the earliest stage at which the maturation cycle is affected by TSE infection.
PrPd labelling was not associated with regions of the FDC dendrites that retained a fine line of Ig-containing immune complex (Fig. 3A), strengthening the suggestion that this novel abnormal FDC morphology represents the earliest stage at which TSE infection affects the FDC maturation cycle.
Our data suggest this previously unrecognised morphology represents the initial stage of an abnormal FDC maturation cycle, whereby early PrPd accumulation induces abnormal dendritic folding, and leads to loss of normal linear immune complex retention within the extracellular space between dendrites.
This organization of germband morphology represents the structure that is typical of arthropod taxa at the so-called ordinal or class level.
Arthroaspis falls basally within the clade including the trilobites, Phytophyilaspis, and Sinoburius, indicating that its helmetiid-like tergum morphology represents the plesiomorphic tergite morphology of a large clade including the pygidium bearing Helmetiida, Nektaspida, and Trilobita.
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The platey morphologies represent the aluminosilicate substrates with which the Fe-nanoparticulates are usually associated.
The study of microglia and macrophage (M/M) morphology represents a key tool to understand the functional activation state and the pattern of distribution of these cells in acute brain injury.
Possibly, the primed microglial morphology represents microglia, which are in a more sensitive state to subsequent stimuli, commonly referred to as 'second hit' [ 30, 31, 59].
Specifically, we test the hypothesis that adult foot morphology represents an adaptive condition, as previously proposed [ 31, 34].
Thus, the natural variation of S. cerevisiae cellular morphology represents a set of multiple independent traits with different sources of variability.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com