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Collectively, the mammalian VLPs resemble the real viruses in particle size, morphology, protein composition, and glycosylation profiles and therefore offer great potential as safe and effective influenza vaccine antigens.
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In addition to similarities in particle morphology and protein composition, RVFV and the RVF-VLPs are antigenically indistinguishable and respond similarly to inhibitor compounds [14].
Using AQP4-null mice, we analyzed the effect of the absence of AQP4 on the morphology and protein composition of sarcolemma as well as on the whole skeletal muscle proteome.
Furthermore, we also examined how the atg32Δ mutation influences mitochondrial morphology, protein and lipid compositions, oxidative damage, and function.
Exosomes, microvesicles and other extracellular vesicles differ in properties such as size, morphology, buoyant density, and protein composition [ 11].
XMRV is almost identical with MoMLV in terms of genome sequence, protein composition and morphology, suggesting that these two viruses might have a highly similar catalytic mechanism as well.
Not only the protein composition, but also the morphologies as well as (sub) cellular and regional distributions of inclusions can be correlated to specific disorders and subtypes of disorders [ 1- 3].
RVFV and RVF-VLPs were harvested by ultracentrifugation and analyzed for particle morphology by transmission electron (Fig. 1) and protein composition by immunoblot (Fig. 2).
One of the important problems of chromosome biology is to understand the relationships between the morphology of the chromatin and the DNA and protein composition.
The resulting virus particles have a regular protein composition and no changes in their morphology were obvious by electron microscopy, but their hemolytic activity is reduced indicating a defect in membrane fusion.
While the characterization of the proteinaceous filaments by immuno-EM revealed the gross morphology of the filaments, it left unanswered the question of the protein composition of the static filaments.
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