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These cells exhibit neuronal morphology, marker expression, and electrophysiological properties.
First, MSCs were defined by their morphology, marker expression, and differentiation ability.
Under these conditions, we found a strong association between epithelial or spindle-cell morphology, marker expression (CK14, CK18, vimentin, and EpCAM), and the proportion of CD44+/CD24- cells.
The hESC-derived RPE cells exhibited a morphology, marker expression, and function similar to those of authentic RPE and restored retinal structure and function after transplantation in vivo.
Successful reprogramming of prostate tissue into Pro-iPSCs and bladder and ureter into UT-iPSCs was demonstrated by characteristic ESC morphology, marker expression, and functional pluripotency in generating all three germ-layer lineages.
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The IPSC lines A and B (derived from fibroblast lines A and B), also displayed very similar morphologies, marker expression, global methylation profiles, capacity for teratoma formation, and telomere elongation[7] and were used in this study between passages 5 8.
The newly formed β cells resemble islet β cells with regard to cellular morphology, marker gene expression, and insulin secretion in response to glucose challenge.
hPSCs cultured as colonies in conditions supporting self-renewal demonstrated the morphology and marker expression of undifferentiated hPSCs.
Similarly, hCNS-SC can be expanded either as neurospheres or in extended adherent monolayer with a morphology and marker expression profile consistent with radial glia NS cells.
The purpose of the current study was to elucidate a simple method of isolation and differentiation of EPCs by defining the endothelial morphology, surface marker expression, and proliferative capacity of EPC outgrowth from canine peripheral blood mononuclear cells (PBMCs).
END2 and PYS2 cells have been described previously, based on cell morphology and marker expression [1], [4], [5], to be similar to visceral endoderm (VE) and parietal endoderm (PE), respectively.
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