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Among compelling applications of this approach are its use for diagnosing disease based on measuring cellular morphology both in situ and in vitro and its use as a precision tool for cell biology experiments, leading to improved understanding of the basic functions of the cell and the origins of dysfunction due to disease.
Pantethine administration was able to completely rescue the mitochondrial morphology both in the PNS and CNS.
It can influence the fracture morphology both in propagation path and failure pressure greatly.
Electric fields are a versatile and easy way to control long range orientational and translational order of nanostructured block copolymers as well as miscibility and morphology both in thin films, bulk and solutions [33].
In the mouse FXS model, minocycline promoted the maturation of hippocampal dendritic spines towards normal morphology, both in vitro and in vivo, and repressed anxiety and memory defects in an elevated plus-maze test (Bilousova et al., 2009).
The goal of the research presented in this article is to investigate what the biophysical requirements are for generating the typical "takotsubo" morphology, both in terms of potential dominant change in protein regulation and the spatial gradient required to produce an apical ballooning phenotype.
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Despite these differences in morphology, both the nasal SCCs and the tracheal SCC brush cells utilize the chemoreceptive transduction cascade first described in taste buds.
The micrographs show similar morphologies, both in the presence and absence of sorbitol.
SOX2 nuclear labelling was observed in a high proportion of NECs and GFAP cells of all morphologies, both in the vicinity of the ICE injury and in distal cortex and white matter, and in lesions of all ages (Fig. 7B).
Furthermore, unlike transgenic approaches, electroporation of a sensor would be ideal to resolve the detailed morphology of single cells both in slices and in vivo.
Interestingly, the plasmid cured strain exhibited small colony morphology and displayed slower growth both in vitro and in vivo.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com