It also emphasizes a justifiable need for replacing current morphology based classification systems of breast cancer by a molecular classification that may be more relevant prognostically [ 7].
These findings suggest that global gene expression signatures can be an important adjunct to the morphology based classification schemes for serous papillary tumours currently used.
The cancer incidence data available to us were coded by ICD-O and this allowed us to employ a cancer morphology based classification system, rather than the usual cancer site-based figures presented in other studies.
Despite differences between TUD and morphology based classification, TUD phylogeny retains utility in understanding host-phage co-evolution and deviation in patterns of nucleotide usage in certain viruses since their divergence from recent common ancestors.
This morphology-based or phase interface based classification has been successfully applied to many other applications e.g. colony boundary strengthening of fully lamellar TiAl alloys ( Schnabel and Bargmann 2017).
The results of the classification were compared with the actual surface morphology based on high-resolution orthophotos, aerial photos, and field surveys.
For instance, gene expression profiling has been explored as a potential tool to improve the accuracy of tumor classification and prognosis [30], which so far are largely histology and morphology based.
Across many groups of animals, morphology-based classifications have been frequently revised based on new molecular phylogenies by identifying previously undetected homoplastic evolution of morphological characters (e.g. in the flatworm family Capsalidae [ 12], the genus Dracus [ 13], the lanternfly family Fulgoridae [ 14], or in Brazilian worm lizards [ 15]).
To help clarify species and subspecies boundaries, and to establish whether morphology-based classifications were consistent with evolutionary relationships, the phylogenetic relationships within the genus Nycticebus were investigated by Chen and colleagues using DNA sequences derived from the mitochondrial markers D-loop and cytochrome b.
To help clarify species and subspecies boundaries, and to establish whether morphology-based classifications were consistent with evolutionary relationships, the phylogenetic relationships within the genus Nycticebus have been investigated using DNA sequences derived from the mitochondrial markers D loop and cytochrome b.
