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The morphologies of differentiated MEFs from wildtype and Fsp27−/− mice are very different.
RT-PCR results and cell morphologies of differentiated cells with and without beacon indicated that there was no change in the ability of stem cell differentiation (unpublished data).
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A restricted number of them reached the OB granular region, and displayed the morphology of differentiated neurons (not shown).
We also evaluated the morphology of differentiated neurons after miR-663 overexpression by measuring the length of neurites.
Among cells with morphology of differentiated cells, H-NE uptake-positive cells with neuronal morphology were observed only, indicating that in these cultures functional NET was limited to differentiating neuroblasts/neuronal progenitors.
This result indicates that although TWIST cannot sustain a full reversal of differentiation (cell cycle re-entry) in the absence of growth factors, it is capable of reversing the morphology of differentiated muscle cells.
Increased staining was observed in the cells that underwent glial differentiation with a characteristic change of morphology indicative of differentiated state.
Figure S1 shows the morphology of fibrocytes, differentiated from CD14+ monocytes under SF conditions, following the addition of serum.
The images in Figure 1 nicely document the morphology of various differentiated cell types.
However, the morphology of the differentiated O4+ cells varied with O2 concentration.
Examination of the biopsy specimen from primary gastric tumour revealed that it has the characteristic morphology of poorly differentiated adenocarcinoma accompanied by stromal cells.
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