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Overall the results suggest that oncocytes (Hürthle cells) arise in response to a chronic inflammatory milieu within the thyroid gland, forming a spectrum of morphological variants, with an "autoimmune Hürthle cell" at one end and a "neoplastic Hürthle cell" at the other end of the spectrum.
In summary, we report that thyroid oncocytes (Hürthle cells) arise in the thyroid gland in response to a chronic inflammatory milieu concomitant with LMP2 over expression, and suggest they form a spectrum of morphological variants with an "autoimmune Hürthle cell" at one end and a "neoplastic Hürthle cell" at the other end of the spectrum.
Less obvious progress, however, has been accomplished concerning the species level of algal taxonomy, when there is an abundance of morphological variants with uncertain taxonomic status.
Several morphological variants with contrasted transformation potential have also been observed during the proliferation and maintenance of embryogenic calli in cotton [ 57].
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Classic ILC may be admixed with one or more of these morphological variants or with tumour cells of a tubular growth pattern (tubulo-lobular carcinoma).
Confocal microscopy revealed that all three morphological variants were 'hollow' with respect to SDL.3D10 immunohistochemistry (Fig. 1B, inset).
This category includes lymphomas with centroblastic, immunoblastic, and anaplastic morphology as common morphological variants [ 1].
Rule-based approaches address some of the limitations of dictionary-based approaches by dealing with morphological variants not covered by the latter approaches [ 27].
Most are of serous or mucinous type with other morphological variants being much more uncommon.
3, 5 DI-SCLE is the most common form of DILE, with two major morphological variants: annular polycyclic and papulosquamous, both typically occurring on sun-exposed areas corresponding to the V-neck, back, shoulders and extensor sides of the upper extremities.
Rule-based methods resort to handcrafted patterns and rules to deal with the different types of morphological variants.
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