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The arthroconidia inhaled by a susceptible host have phenotypic morphological transition from mycelial to the parasitic phase presenting diverse morphologies.
These particular phenotypic changes were also observed in Slu-01 cells, which exhibited an obvious morphological transition from a rounded or cobblestone-shaped, epithelial-like morphology to spindle-shaped fibroblast with the loss of its cell polarity, cell cell adhesive interactions and junctions when transfected with pcDNA3.1-AEG-1.
In conclusion, arthroconidia inhaled by a susceptible host engage in a phenotypic morphological transition from the mycelial to the parasitic phase presenting diverse morphologies, and according to the diversity of parasitic forms observed in specimens from patients with coccidioidomycosis, it is possible to consider Coccidioides as a polymorphic fungus in its parasitic phase.
Figure 1 shows the model of morphological transition from quadrupedalism to bipedalism.
Images of particles resuspended two (c) and three (d) times in 3 mM aqueous Fe(II) show a morphological transition from rod-like precipitates to spherical particles.
Tyrosol and farnesol are QS molecules produced by C. albicans which accelerate and block, respectively, the morphological transition from yeasts to hyphae.
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Degradation-induced morphological transitions from worms to spheres are quantitated in terms of decreasing contour lengths.
The phase and morphological transitions from TiO2 to Li4Ti5O12 were characterized using X-ray powder diffraction and transmission electron microscopy.
Morphological transitions from diffusive to massive (partitionless) growth are observed on increasing the initial mole fraction of aluminum.
When inoculated into cell culture medium, the purified proteins fetuin-A and albumin fail to induce mineralization, but they will readily combine with exogenously added calcium and phosphate, even in submillimolar amounts, to form complexes that will undergo morphological transitions from nanoparticles to spindles, films, and aggregates.
Regardless of the origin of ovarian mucinous carcinoma, morphological transitions from cystadenoma to a mucinous borderline tumor (MBT) to intraepithelial carcinoma and invasive carcinoma have been recognized for some time, and an increasing frequency of KRAS mutations at codons 12 and 13 has been reported in cystadenomas, MBTs and mucinous carcinomas, respectively [ 63– 63].
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