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Co-stimulation of TGF-β and BMP-7 led to a reversal of the prior morphological transformation with a predominant epithelial phenotype.
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Both HT-29 and Caco-2 displayed morphological transformations with cetuximab treatment.
The micrographs showed that a morphological transformation occurred with the formation of carbon structures in the shape of micrometric spheres.
For instance, Oliveri et al. [5] applied transcranial magnetic stimulation (TMS) while their participants performed a morphological transformation task with action-related nouns and verbs and found that activity in the left primary motor cortex (M1) was enhanced regardless of the word's grammatical class.
We show, for the first time, that constitutive activation of either Grb2 or Shc signals in IEC-6 cells, promotes morphological transformation associated with down-regulation of E-cadherin, as well as increased cell growth, loss of growth contact inhibition, anchorage-independent growth, and resistance to serum deprivation and anoikis.
No morphological transformation was seen with either MWCNTs or quartz in cells or PSF.
PAD1-expressing cells then undergo morphological transformation to stumpy forms, with an anticipated lifespan of 49.9 ± 5.7 hr.
Finally, the morphological transformation of cells transfected with siRNA has been examined by immunohistochemistry for β-tubulin 72 h after transfection.
Consistently, we showed that Mocetinostat application induced E-cadherin expression and surface translocation of β-catenin associated with morphological transformation of atrial CD90+ cells toward epithelial-like phenotype.
Particles of insoluble nickel compounds were phagocytized by C3H/10T1/2 mouse embryo cells and induced morphological transformation in these cells with the following order of potency: NiO (black) > NiO (green) > nickel subsulfide.
The observations from human ovarian cancer tissues suggests that loss of GATA4 expression often precedes the loss of GATA6, and the loss of GATA6, correlated with the loss of Dab2, associates with epithelial morphological transformation.
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