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This morphological switch of myosin heavy chain isoforms can indirectly be verified by calculation of the twitch-to-tetanic force ratio [ 9].
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On the one hand, serum promotes morphological switching of Candida from yeast to hyphal forms, which is necessary for its evasion of phagocytosis and organ colonization [ 7].
Importantly, control hyphae and hyphae developed in the presence of PK E6/E7 VECL could not be distinguished in terms of the timing of the morphological switch, rate of hyphae development, or length of hyphae and 1(c)).
On exposure to 37°, P. marneffei cells undergo a morphological switch to uninucleate yeast cells.
At 37° P. marneffei undergoes a morphological switch to grow as pathogenic uninucleate yeast cells that divide by fission.
The number of cells undergoing this morphological switch increased as time of incubation with ACh or CCh increased (data not shown).
This resulted into a relative muscle cell hypertrophy at day 14 after injury and an enhanced morphological switch towards a slow-twitching phenotype of muscle.
Consistent with the observed morphological switch, kaempferol significantly reduced the expression of EMT-TFs in both H358_EMT and H358_R cells and concomitantly downregulated the stem cell genes in H358_R cells.
Kaempferol-dependent abrogation of chemoresistance is likely due to the reversal of the EMT, as kaempferol treatment effectively induces a morphological switch from mesenchymal-to-epithelial phenotype and concomitantly reduces the expression of EMT-TFs and mesenchymal cell markers.
Infection of epithelial cells by C. albicans requires adhesion of yeast form cells to the surface of epithelium, a process that aids in inducing a morphological switch resulting in hypha formation.
When the polymer was transferred to aqueous medium through solvent exchange technique, micellar assemblies were obtained, with a morphological switch from "flower-like" crew-cut micelles to large compound vesicles upon partial quaternization of 2VP block.
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