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Increased ductal replication, most frequently due to chronic pancreatitis, is considered to be the first stage in a progression of morphological stages that may lead to pancreatic adenocarcinoma [ 32].
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The fine grain of our cell lineage observations also allows us to relate these data with the even finer morphological detail of confocal laser scanning microscopy-derived morphological descriptions of certain ascidian embryonic stages that recently became available [ 53, 54].
The evolutionary transition from phagotrophy to phototrophy is therefore non-trivial, and the intermediate stages that bridge the morphological traits associated with these two lifestyles are important to understand.
We conclude that bioengineered teeth commonly exhibit morphological stages characteristic of naturally forming teeth.
A post-processing stage that includes morphological filtering and a weighted scheme to select the most salient object follows.
Although the morphological stages of Purkinje cell dendritic development have extensively been characterized, relatively little is known about the molecular mechanisms that underlie these processes (24– 24).
The data indicate that microglial cells are involved in the death of dentate granule cells by a phenomenon consisting of four morphological stages (see drawings in Fig. 10).
E-cadherin deregulation occurs in the earliest morphological stage of lobular tumourigenesis (that is, ALH) and is frequently and irreversibly driven by genomic alterations targeting its gene, CDH1 (located at chromosome 16q22.1).
This suggests that for the same morphological stage of panicle development, stamen differentiation, and therefore floret differentiation, might be delayed in O. glaberrima with respect to its wild relative, O. barthii.
This supports the hypothesis that for the same morphological stage, all terminal and lateral meristems had acquired the spikelet fate in O. barthii, whereas in O. glaberrima few had done so.
This morphological stage includes the first rejoining of nerve endings, supporting the intuitive conclusion that this connection is required to link the response of the two siphons.
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