The tumor clinic morphological stages were determined according to the standard tumor TNM classification systems of the International Union Against Cancer (edition 7).
The ability to associate changes in the transcriptome with distinct morphological stages was a valuable tool enabling us to capture and offer a plausible interpretation for the dynamic changes in gene expression and abundance.
Figure11 and Table2 show the segregation results when morphological image processing smoothing stage is applied.
The warm stratification stage is a morphological dormancy release period when the radical, hypocotyls and cotyledon are formed.
Combined with previous observations showing that even poor quality blastocysts, when euploid, retain a significant implantation potential (Capalbo et al., 2014a, b), these data further demonstrate the importance of considering all blastocysts for the biopsy and CCS regardless of their morphological appearance, provided that the expanded stage is reached.
Since the resulting mask map often contains broken auditory element groups after grouping stage, a smoothing stage is proposed based on morphological image processing.
These morphological stages can be easily differentiated on morphological grounds by light microscopy, since epimastigotes are broader and have a quite rigid body, while trypomastigotes are slimmer and present a vigorous wavy movement of the whole body.
Developmental stages and the morphological phenotype in each stage are shown in Additional file 9. Overall, expression intensity was high in the ABCE to ABCH subfamilies.
Together, these morphological observations suggest that mitochondria remaining in nerves and muscles at this stage are structurally normal.
E-cadherin deregulation occurs in the earliest morphological stage of lobular tumourigenesis (that is, ALH) and is frequently and irreversibly driven by genomic alterations targeting its gene, CDH1 (located at chromosome 16q22.1).
