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Both polymorphisms of MTHFR may be involved in the morphological specification of primary varicose veins and contribute to the development of complicated disease.
A strong influence of genotypes at MTHFR c.677C>T and c.1298A > C on the morphological specification of primary varicose veins and progression towards complicated disease is suggested.
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In Text S10 we formalize this intuition as a mathematical model and derive a linguistic learnability (fitness) landscape for languages over varying levels of morphological specification and proportions of adult learners.
We tentatively propose that the level of morphological specification is a product of languages adapting to the learning constraints and the unique communicative needs of the speaker population.
Nevertheless the higher rate of adaptation in the young genes might be consistent with the ideas that lineage-specific genes may drive morphological specification, enabling organisms to adapt to changing conditions (Khalturin et al. 2009) and also with the observation that young genes tend to be less functionally important.
It would be difficult to reconcile this morphological specification with the structural requirement for protection, which is the tight sealing of the valves.
Finally, it is shown that automotive designers impose morphological specifications obtained by the belt grinding process to prevent scuffing of the motor parts.
As in our previous study, we obtained very good contrast and morphological delineation, within the specification of a 5- μm spatial resolution, using transgenic expression of YFP in motor neurons.
Specifically, the specification of pieces and tools can be achieved through the use of new operations describing geometric processes of cutting and reconstruction (erosion and dilation respectively, in morphological terms).
The classification schema introduced by Hippocampome.org [11] defines neuron types based on their properties, starting from morphological patterns and with the added specification of molecular and electrophysiological features.
These cells might participate on the morphological changes during prism formation and early axis specification of plutei, because they were absent from the ventral ectoderm of C. subdepressus; a region that remained flat until the formation of the larval mouth.
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