Tumor cells display functional, developmental and morphological similarities to their site of origin (Lobo et al., 2007; Sell and Pierce, 1994).
These data also support the concept that the subchondral bone is the site of morphological changes that are part of the OA disease process [ 5, 8, 10- 18, 18, 34], and provide further evidence in favour of the concept that therapeutic intervention to reduce these changes may also prevent the development of cartilage lesions.
In both cases, a large number of signaling, structural, and transport proteins localize at the site of the morphological change [2], [3].
These data hence better characterize and confirm electrographically the occurrence of spontaneous clonic seizures in the absence of convulsant in Dcx KO mice and localize seizure onset to the hippocampus, the site of visible morphological abnormalities.
Decidual sections provide access to the maternal environment, site of intense morphological, physiological and immunological reorganizations.
We failed to detect morphological defects at the attachment site of the intestine to the rectum in any of the mutant backgrounds examined.
Brain and other nervous system (NS) tumours are a group of neoplasms that vary in terms of their site of origin, morphological features, genetic alterations, growth potential, invasiveness, tendency to progression and recurrence, and response to treatments [ 1- 4].
Under OA conditions, the subchondral bone is the site of numerous dynamic morphological changes.
We tried to extract factors that might potentially influence the histopathological characteristics of the tumors: we found that the morphological characteristics were related to the site of involvement.
