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Of particular interest, experiments conducted to silence the expression of E-cadherin not only showed a morphological shift from an epithelial to a fibroblastoid phenotype, characteristic of EMT, but also a concomitant increase in invasive cell behavior [5].
In addition, neointimal regression occurred with a morphological shift from a layered pattern to a homogeneous pattern.
Previous studies on cell culture systems, demonstrated mainly by morphological and biochemical data, have indicated that NAC addition stimulates proliferating cells to go into differentiation phase [ 1]. Figure 1 displays a scanning electro micrograph image of the cell types tested and demonstrates the morphological shift from proliferating to differentiating cells after addition of NAC.
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This prediction is supported by both the inverse relationship between morphological traits and tree cover and previous research on this species showing morphological shifts resulting from deforestation [14].
This morphological shift in stamen number usually involves only the increase of sterile stamens from the mid-upper to both the mid-upper and lateral/ventral stamens with the length of corolla tube unchanged in most groups of Gesneriaceae.
This morphological shift may be the result of an increase in the Flory–Huggins interaction parameter between the two blocks, a change in the volume fraction, and/or a loss of chain mobility resulting from hydrogen-bonding after grafting.
Considering all measured birds without assigning them a priori to any sub-species we found a clinal morphological shift.
Figure 4 demonstrates that this morphological shift only occurred in areas of cellular damage.
The morphological evolutionary shift from tetrandrous to diandrous flowers has occurred several times in the Old World Gesneriaceae, such as the shift from tetrandrous Oreocharis to Opithandra with only two lateral fertile stamens and from tetrandrous Anna to diandrous Lysionotus with both the mid-upper and lateral stamens aborted [ 14, 15, 18].
These morphological shifts were worked out through trial-and-error, with technical progression and the seeming whims of certain pros.
Hall (1997) suggests that many arguments against the existence of the phylotypic stage are based on heterochronic (or timing) shifts in development, not morphological shifts.
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