Down-regulation of lamin A/C in breast epithelial cells led to morphological deformation, resembling that of cancer cells, as observed by immunofluorescence microscopy.
We found that the nuclei of BMP-12-treated cells exhibited morphological features resembling the organization of cells in native tendons, while untreated MSCs did not.
In summary, our findings show that loss of Frabin/Fgd4 in the mouse leads to electrophysiological and morphological abnormalities resembling the hallmarks of CMT4H, thus establishing Fgd4 − / − mice as an animal model for this disorder.
However, a similar dystrophic phenotype resembling morphological signs of aging has not yet been seen in the rodent brain.
Interestingly, the lack of Pttg2 result in morphological changes resembling those appeared in the presence of elevated PTTG1 levels.
The collection is available online and in chart 42 (Fig. 12) seed beads with similar colours and sizes as the Mapungubwe Oblates can be seen, as well as black beads that on morphological parameters resemble many of the black beads in the older series beads.
Their morphological features resembled that of lymphocytes but whether fish B lymphocytes display adherence properties to nylon wool, as their mammalian counterparts, remains to be investigated.
In the present study, the glomeruli showed irreversible lesions such as adhesion and sclerosis as well as severe podocyte injury, and these morphological changes resemble those of human focal segmental glomerulosclerosis (FSGS).
The tumor cells have morphological characteristics resembling tanycytes, a special subtype of ependymal cells.
While these morphological changes resemble the acquisition of a more differentiated phenotype at the edge of the wound, we could not detect the upregulated expression of cytokeratin 1 or loricrin in the basal layer (data not shown), which would have supported the activation of terminal differentiation programs.
