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The gross morphological profile of RCC can further delineate subtype, with clear cell RCC typically exhibiting exophytic growth patterns.
The morphological profile of a cell can be observed by combining forward light scatter (FSC) and orthogonal or side light scatter (SSC).
Using cells from 10 melanoma patients, we investigated the morphological profile of cells harvested on day 7 of culture after stimulation with LPS.
Our clonal analysis of epicardial-derived cells identified cells with the molecular marker and morphological profile of vascular pericytes as being lineage related to caSMCs.
Thus, the morphological profile of linked features differed significantly between FGCB and FGCB-HI, indicating distinct entities, with FGCB almost exclusively found in the unexplained group.
Compared to healthy controls, the morphological profile of structural changes was more widespread in PD-MCI subjects with cortical thinning spanning across the frontal, parietal, and occipital cortex as well as the cingulate cortex.
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Green: rounded cells with aspect ratio less than 2. Red: elongated cells with aspect ratio greater than 2. DIGME allows continuous confocal imaging at the single cell level, therefore we can track the morphological profiles of the diskoid over time.
Using standard Drosophila genetic tools and recently developed imaging software, we carried out studies examining the morphological profiles of the individual FruM/OA neurons.
Here we extend our previous behavioral and anatomical findings by utilizing several different experimental approaches to: (i) selectively enhance, rather than reduce OA neuronal function; and (ii) precisely alter the sex of a subpopulation of these neurons; (iii) describe the morphological profiles of the three FruM/OA neurons in 3-dimensions.
Levy and Siegal computed phenotypic potentials from CalMorph morphological profiles of systematic gene deletion mutants [ 8].
Extending our study to the morphological profiling of diploid hybrids would be interesting in this regard: additivity would suggest gradual drift of cellular regulations whereas non-additivity would imply more discrete phenotypic changes possibly emerging from loss of function mutations.
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