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Although the screen used by Seiler and Plamann identified morphological mutations in NCU00651 with high frequency, their screen was not designed to find TS lethal mutations.
The characterization of both TS lethal and TS morphological mutations in the same gene in Neurospora emphasizes the value of traditional mutant hunts.
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The map proved effective in mapping classical morphological mutations of A. majus.
Of course, de Vries (1901 1903) did not have any idea about chromosomal variation, but his study of morphological mutations stimulated other workers to study the chromosomal mutations and their importance in speciation.
In agreement with the high proportion of embryo lethality, all M2 families segregated for easily visible morphological mutations (data not shown).
In an extreme case, a morphological mutation causes males to lack the structures on the forewing that are needed for song; thus, males with this mutation are silent.
Rutherford and Lindquist (1998) observed that a mutation in one of the chaperones, the so-called heat-shock protein Hsp90 in Drosophila melanogaster, increases morphological variation in multiple traits, including wings, legs, eyes, and abdomen.
This loss occurred by a morphological mutation affecting wing structure instead of a behavioral suppression of the song.
In PD patient fibroblasts, only the morphological effects of mutations in Parkin have been studied so far revealing that the degree of mitochondrial branching was higher than in controls [21].
This report is the first account of two closely related crop species converging on a single morphological feature through mutations in different genes.
As not all hemisegments in homozygous mutant embryos exhibit this latter phenotype, we assessed whether there is any correlation between the de-repression of a specific gene and the morphological defects associated with mutations in jumu or CHES-1-like.
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