Consequently, for the quantitative risk assessment of workplace chemicals, it can be assumed that the dominant effects caused by locally acting chemicals are biochemical and morphological alterations of the RT.
Numerous factors have been implicated in the cartilage repair process, but the uncontrolled delivery of these factors may not only reduce their full reparative potential but can also cause unwanted morphological effects.
A secondary callus regeneration step provides a convenient way to rescue transgene expression without causing undesirable morphological effects, which is essential for experiments that use transformed plants in the analysis of ecologically important traits.
Therefore, the H3K37A mutation probably affects chromatin binding by multiple HMG proteins during conditions of reduced TORC1 activity to cause these more severe morphological effects.
For example, treatment of zebrafish embryos from 0 to 24 hr after fertilization with flusilazole, a known developmental toxicant, caused a concentration-dependent response in morphological effects (Hermsen et al. 2012).
Distinctive morphological effects, the most common of which was reduced neurite outgrowth (Fig. 7E,F,H K), were caused by both active and inactive compounds.
Since there are no significant increases observed in liver and kidney parameters, therefore strongly suggest that there are no obvious detrimental effects or morphological disturbances caused by the daily oral administration of OS-EL for 28 days, even at the highest tested dose of 1000 mg/kg.
Although, mutations in LOB genes do not cause conspicuous morphological changes, expression of LOB outside of its normal domain has several morphological effects [18].
Large catalytic and morphological effects were found.
