Due to the morphological effects, the rod-like BSA-modified MNPs were expelled from the lung more quickly, meanwhile, the rod-like particles were expelled from the spleen more slowly (Fig. 4).
Our previous work has indicated the importance of direct interactions between epithelium and stroma to produce morphological effects (the effects are not achieved using stromal conditioned media), therefore the presence of both cell types is critical [4], [15], [25].
Distinctive morphological effects, the most common of which was reduced neurite outgrowth (Fig. 7E,F,H K), were caused by both active and inactive compounds.
The macro-structures are not much impaired by the crystallization nevertheless the morphological effect of the heating process is still obvious.
The morphological effect of the irx mutations led us to hypothesize that the main reason for dwarfed growth in irx mutants is the collapsed vessels, and that specifically restoring xylan biosynthesis in vessels would therefore complement the mutations.
In detail, α-Fe2O3 films with morphologies of nanoparticals and nanorods have been compared and the morphological effect on the photoelectrocatalytic activity has been discussed.
Furthermore, whereasoverexpression of RB blocks the morphological effect and the suppression of E-cadherin expression [ 66], downregulation of RB induces EMT [ 67].
In this study, trypan blue assay, which was sensitive to permeability of membranes, was further used to verify the observed morphological effect at the concentration of 100 μg/mL.
Treatments with BzATP or the vehicle solution had no visible morphological effect on the skin (Fig. 8A), and histological evaluation showed no differences in cross sections obtained from the BzATP-treated or control skin areas (Figs. 8B, C).
Though minor at the genetic level, these changes result in a substantial morphological effect, namely the loss of fruit cases around grains (Fig. 3).
