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Hematoxylin and eosin staining showed no morphological disruption of the retina in the in vivo study.
Notably, statins induced a unique morphological disruption of the cultured neurons.
Further studies of the Hyp mouse show severe morphological disruption of the growth plate which can be corrected by the administration of cathepsin inhibitors [16].
It was reported that morphological disruption of myofibrils was associated with the magnitude of decrease in muscle function (Raastad et al. 2010).
Administration of drugs by intravitreal injection can result in morphological disruption of the retinal structure, caused by the injection procedure and tissue inflammation.
The accumulation of several family members at the PVM and the morphological disruption of the vacuole suggest an effector action at this site.
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The severity of morphological disruption morphology was scored according to an arbitrary index with 0 being normal and 4 being severely disrupted (Table 1).
To assess the degree of morphological disruption, we examined the pattern of actin and ElaV expression in each eye epithelium.
Using this metric, we demonstrated a statistically significant rescue of CagA morphological disruption by co-expression of sqhA21 (Fig. 3G).
Some of these subtleties may be attributed to degrees of morphological disruption.
To quantify the degree of morphological disruption in eye epithelia, confocal stacks were imported into Image J (NIH), 3D reconstructions were made using Volume Viewer, and images were thresholded to gain area measurements of deep ElaV cells.
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