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Surprisingly, we find that in contrast to its protective role in many aging models autophagy is driving morphological deterioration of the Drosophila adult epidermis (comparisons of epidermal morphology quantifications from different time points and genotypes are compiled in Figure S3).
The overall results show that the morphological deterioration of the protective layers resulting from ageing is always associated to a drop of the performance in terms of corrosion protection.
In day 8 tph-1 mg280) tph-1 mg280ges, morpharynxcal deterimageson simorphological of normal aging was evideteriorationing for the convergence in age-similarwito fem-1(hc17) conthats.
First, we show that NMJs in dilute lethal mice (referred to as 'dilute mice' in the following) lacking functional myosin Va exhibit a postnatal, time-dependent morphological deterioration that correlates with the dramatic aetiopathology leading to lethal seizures at around P21 (Fig. 1, Fig S1, Movies S1, S2, S3).
The epidermis undergoes a dramatic morphological deterioration with age that includes membrane and nuclear loss.
Unexpectedly, we observe that autophagy both correlates with and drives morphological deterioration of an aging adult tissue.
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SEM investigations on the archaeological bow case preserved in ice (Samples 2 and 3) showed significant differences in morphological signs of deterioration in terms of the cells present in the different parts of the bow case.
Fourier transform infrared spectroscopy confirmed an adequate physical interaction between bitumen and wPET/GTR blend, while morphological analyses suggested deterioration of interaction upon increase of GTR content, which can be ascribed to the cross-linked structure of GTR.
Results. 1 α,25(OH)2D3 ameliorated CG-induced morphological and functional deterioration in animal model, along with CG-induced upregulation of α-SMA and downregulation of E-cadherin expression.
The diagnosis of CAD was based on functional and morphological (biopsy confirmed) deterioration of a renal allograft at least 3 6 months after transplantation.
Continuous exposure to conventional bio-incompatible dialysate, which is acidic and contains large amounts of glucose degradation products (GDPs), is now thought to be one of the main causes of peritoneal morphological and functional deterioration [ 6, 7].
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