Suggestions(5)
Exact(4)
A regression analysis [ 17] was carried out on the following: normal morphology with PR; parameters of SCSA with PR, with the incidence of specific morphological defects, with sperm survival and with age of stallion.
Extensive apoptosis was observed in the head region of the morphants, thus correlating the morphological defects with apparent cell death.
(4) Since the generation of functional truncated Ptenb protein could not be excluded in the ptenb mutants [32], the ptenb−/− embryos was treated with ptenb tMO1 and these mutant embryos showed similar morphological defects with wild type embryos.
Analysis of the EADs revealed an accumulation of mutant tissue basally, reduced differentiation (Fig. 6Ci,Cii and arrows in 6Di,Dii) and morphological defects with accumulation of F-actin (Fig. 6Ciii,Civ and arrowheads in 6Diii,Div; quantified in 6F).
Similar(55)
In addition, morphological defects induced with M6-RNAi lines were first observed at stage 9. Thus, while oogenesis apparently proceeded relatively normally from germarium through stage 8, morphological defects triggered by downregulated M6 expression became detectable at later stages.
The AS1 inhibitor morphological block appeared reminiscent of morphological defects seen with the vaccinia redox proteins, A2.5, E10, G4, phosphoprotein A13 and LY294002 pretreatment [20], [22], [26], [28], [48].
DBI is a particularly promising candidate for the regulatory pathway responsible for the brain and morphological defects associated with ZS.
Defects in membrane potential, respiratory distress and inefficient transport can all secondarily contribute to the morphological defects associated with mutant Htt expression.
Embryos that exhibited gross morphological defects associated with RNA toxicity or morpholino toxicity or other idiopathic growth defects were excluded from the analysis.
Flies lacking yar RNAs are viable and show no overt morphological defects, consistent with maintained transcriptional regulation of the adjacent yellow (y ) and achaete (ac ) genes.
As not all hemisegments in homozygous mutant embryos exhibit this latter phenotype, we assessed whether there is any correlation between the de-repression of a specific gene and the morphological defects associated with mutations in jumu or CHES-1-like.
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