Exact(1)
Moreover, forced expression of let-7 rescues α/β morphological defects caused by temporal ecdysone signalling deficit that was generated by keeping temperature-sensitive dominant-negative EcR and usp mutants at the restrictive temperature during the pupal stage.
Similar(59)
Co-injection of ewsr1a mRNA with the ewsr1a MO or ewsr1b mRNA with the ewsr1b MO rescued the morphological defect caused by MO injection, indicating the specificity of the effect of the ewsr1a and ewsr1b MO (Figure 3A, panels d and f).
Therefore, we conclude that 50 mM mannose provided just after fertilization effectively rescues the morphological and biochemical defects caused by Mpi deficiency.
How potential cell or non-cell autonomous morphological or functional defects cause the distinct deficit in sleep observed in our Drosophila males expressing hMeCP2 in astrocytes is presently unknown.
Vascular defects causing abnormal bleeding are rare.
Altered levels of cardiolipin have been shown to promote severe cristae morphological defects that resemble those caused by loss of MICOS (Xu et al., 2006; Acehan et al., 2007).
It should be noted that morphological defects in notochord cells caused by Eph4ΔC resemble those seen in Cs-lamα/3/4/5 mutants [34].
Although this caused morphological defects, such as small heads and glazed eyes, this rescued maxillary palp formation, confirming that the defect is specific for Wnt6 loss of function.
Some Gal4-VP16 driver lines, as demonstrated for Tg(UAS:myc-Notch1a-intra kca3 myc-Notch1a-intra kca3hsp70l:Gal4-VP16)s1006t myc-Notch1a-intra kca3crossedround expression in tossues unrelathe to Etdogenous gene expression (Faucherre and Lopez-Schier, 201.5hsp70l Gal4-VP16 s1006togicalinefectshowhich might be caused by leakiness of the heat-shock promoter used in the effector line.
This morphological defect was not caused by increased apoptosis as Caspase3 expression was not changed (data not shown).
A truncated form of Eph receptor, which lacks an intracellular protein tyrosine kinase domain, blocks Eph signaling in various organisms [19], [20], [21], [22] and causes morphological defects of the notochord in zebrafish [10].
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