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Exact(6)
Of particular note is the number of mitochondrial proteins whose absence leads to a morphological defect in peroxisomes.
p35 mutant MB projection neurons often displayed one unique morphological defect in aged adults: gross swelling of the proximal region of the axon (Fig. 6).
The most striking morphological defect in strong ap alleles is the complete lack of wing and haltere structures (Butterworth and King 1965).
This technique revealed a morphological defect in the inner ear of mutants, with severely enlarged ES and abnormally expanded cochleae (Fig. 1C,D,F,G), compared with control mice (Fig. 1B,E).
In contrast, wild-type neurons always occupy nearly the entire field of view demonstrating a clear morphological defect in resulting from knockdown of the CDK19 orthologue in these neurons.
Single MICOS subunit deletion causes a characteristic mitochondrial inner membrane morphological defect in cells, consisting of extended, stacked, lamellar inner membranes and a reduction of the number of cristae junctions, with a consequent lamellar mitochondrial shape defect.
Similar(54)
In addition to quantitative alterations in brain morphology, we also observed qualitative morphological defects in both alpha and beta lobes for five of the mutant lines.
tc243 has severe morphological defects in leaf, plant height, inflorescence and flower morphology.
dC1GalT1 mutant larvae have also been shown to have morphological defects in the CNS.
Surprisingly, these mice did not exhibit any apparent morphological defects in the development of normal retinal vasculature.
Expression of KIN-22 induced morphological defects in the pharynx, whereas expression of SRC-1 did not show any overt phenotype in adult.
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