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No significant morphological damage was observed by applying these polymers inside the intestinal lumen.
At the end of 48 h, drastic morphological damage was observed with 5-FU-loaded CP SLN (0.01 μg/mL) compared to other formulations and drug solution.
Normal histological characteristic of glomeruli and tubules, and no morphological damage was observed in the kidneys of sham group.
However, morphological damage was not observed in IPC mice after ischemia when compared with sham-operated IPC kidney).
Morphological damage was noted 24 h post-injury in the AT shortened groups, along with a further decline in relative isometric torque.
Ultrastructural and morphological damage was observed during long exposure 48-722 h), revealing mitochondrial swelling, loss of cristae, vacuolization of ER and dictyosomes.
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Although persistent isometric torque deficit and morphological damage were only evident upon AT shortening, we were unable to precisely titrate the magnitude of damage with stepped increases in AT shortening.
Additionally, severe morphological damages were observed in these study groups.
Renal morphological damages were alleviated after pretreatment of 2 or 4 ml/kg EIso.
These vascular morphological damages were almost completely prevented by captopril (45 ± 0.21 μm versus 58 ± 0.11 μm in the L-NAME group) as well as the plant extract (45 ± 0.4 μm versus 58 ± 0.11 μm in the L-NAME group).
No morphological evidence of damage was observed in the MDCK control monolayer after 3 h of interaction).
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