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However, oral administration of icariin twice per day for 23 days might attenuate cognitive deficits and neuronal morphological damage induced by BCCAO.
Hence, this study was designed to investigate the protective effects of icariin, a major constituent of flavonoids from the Chinese medicinal herb Epimedium brevicornum, on cognitive impairments and neuronal morphological damage induced by permanent occlusion of bilateral common carotid arteries (BCCAO) in rats, and further explore the potential mechanisms.
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Taking into account the results of this study, it is evident that long-term administration of Plantago ovata husk together with acetylsalicylic acid ameliorates the morphological signs of duodenal mucosal damage induced by this NSAID.
To investigate the mechanism of the liver damage induced by hyperammonia, we examined the morphological features of mitochondria by transmission electron microscopy.
Since morphological cell transformation is strongly associated with mutation and/or larger scale DNA damage in C3H10T1/2 cells, the identification of DNA damage induced in these cells by trans-B[a]P-4,5-diol was sought.
Platelets can mediate remote kidney damage induced by pneumonia [207].
We also emphasize the participation of oxidative stress as a relevant component of the renal damage induced by heavy metals and the beneficial effect that some antioxidant drugs, such as vitamin A (all-trans-retinoic acid) and vitamin E (α -tocopherol), depict on the morphological and functional alterations induced by heavy metals.
Damage induces the SOS response [7].
DNA damage induces nuclear actin polymerization.
Thirty minutes of ischemia in non-IPC mice induced severe morphological damage in the kidneys, as compared to sham-operated non-IPC kidneys.
However, the region of IVD cell origin (nucleus pulposus versus annulus fibrosus) was not further specified due to the trauma induced gross morphological damage.
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