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The subsequent morphological conversion of the initially formed submicrometer fibrous aragonite units into well-defined, micrometer-sized, prismatic facets in the skeletal structures of the corals is demonstrated.
Recent studies have demonstrated an important contribution of alternative splicing regulation in the cascade of events characterizing the morphological conversion of tumor cells during epithelial-to-mesenchymal transition (EMT) [ 102], one of the major routes through which cancer cells acquire migratory and invasive potentials [ 103, 104].
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The transient expression of these genes suggests they are not required for long-term viability during starvation and could be involved in the initial stages of conversion of vegetative cells to mating-competent cells which is known to occur during the first few hours of conjugation [12], or in the morphological conversion to slender cells with an elongated cilium.
As shown in Figure 5a, ectopic expression of MKK6EE or SPRY4 knockdown alone (48 h) significantly activated p38MAPK phosphorylation, but failed to promote cell cycle arrest (caspase-3) and efficient morphological conversion (proportions of myotube-like and multinucleated myofiber-like cells) (data not shown).
This design was hypothesized based on a morphological conversion according to the assessment of thermodynamic equilibrium calculated by the contact angle measurements.
Exposure of L. donovani promastigotes to Hsp90 inhibitors GA and RAD induces a morphological conversion from promastigotes to amastigote-like cells that was ascribed to the inhibition of cytoplasmic Hsp90 (Wiesgigl and Clos, 2001).
When Fra-1-siRNA was transfered into HT-29 cells, the mesenchymal-like morphological conversion stimulated by IL-6 was substantially prevented.
Therefore, along with the morphological changes during the conversion of SSCs into oocytes, the epigenetic network was converted into the female germ cell form.
Figure 2 presents a series of SEM images from samples containing 250 μL dispersion of Ag nanowires (20 mg/L) before and after they reacted with different volumes of 20 mM FeCl3 solution, clearly showing the morphological evolution involved in the conversion of Ag nanowires to Ag@AgCl core shell nanowires.
Adipogenesis involves conversion of spindle-shaped preadipocytes to round lipid filled adipocytes, this morphological change requires conversion of filamentous actin to cortical actin which is associated with remodeling of extracellular matrix (ECM) fibronectin (FN) matrix to laminin-rich matrix.
The remodeling of actin fibres and the morphological changes of the membrane were quantified by assessing the intensity of the actin fluorescence after conversion of the coloured pixels to greyscale using the Leica QWin image analysis and processing software.
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