Apoptotic cells display distinct morphological characteristics, including cell shrinkage, chromosome condensation, nuclear fragmentation (late stage), plasma membrane blebbing and the formation of apoptotic bodies, and exhibit biochemical changes, such as the exposure of phosphatidyl-l-serine on the outer plasma membrane (early stage)19,20,21.
Furthermore, the scanning electron microscopy (SEM) imaging of the coculture showed that cells with multiple morphological characteristics, including oval and long rod shapes, coexist in the coculture, whereas only an oval morphology was observed in the axenic sample (Fig. 2b).
Morphological characteristics, including the disruption of membrane integrity, decreased cell growth, cytoplasmic condensation, and cell clumping, were observed in MCF-7 cells treated with AgNPs, whereas control cells remained active.
This "relict" hypothesis was also influenced by the species' unique morphological characteristics (including an elongated snout).
Apoptosis was initially described according to its morphological characteristics, including cell shrinkage, dynamic membrane blebbing, chromatin condensation, and nuclear fragmentation.
According to these studies, the morphological characteristics including border contour and signal intensity of lymph nodes may partly improve the diagnostic ability of metastasis.
The morphological characteristics included keratinization, basal membrane appearance, epithelial thickness, rete ridge length, adjacent rete ridge distance, and regional variation; the immunohistochemical markers included Ki67 (a proliferative marker) and Cytokeratin 19 (CK19; a stemness marker).
Unique morphological characteristics include a massive, finely structured, deep root system capable of reaching 1.2 to 1.5 m.
Dirivultidae belong to the siphonostomatoid copepods and their morphological characteristics include: The body is cyclopiform with length ranging from 0.5 to 1.8 mm (Figure 1A, Figure 2).
In general, apoptotic cells display some specific morphological and biochemical characteristics, including cell rounding and shrinkage, membrane blebbing, chromatin condensation [29], and mitochondrial inner membrane potential changes [30].
During mitosis, NG2 cells maintain their morphological and physiological characteristics, including the highly branched cellular processes and voltage-gated ion channels as well as the active glutamatergic and GABAergic synaptic inputs.
