During its 48-hour intraerythrocytic life cycle, the parasite undergoes major morphological and metabolic changes followed by nuclear division, cytokinesis and merogony to generate up to 36 new daughter parasites.
Morphological changes were followed with Atomic Force Microscopy (ATM) revealing rough nanostructures of the layers.
The physiological and morphological changes were followed in detail throughout the whole period of decline and recovery.
Then, upon ecdysone release from the prothoracic gland, and subsequent onset of metamorphosis, the process begins to reverse as fat body cells undergo autophagy, releasing their lipid contents to help fuel the major morphological changes that follow.
Cell morphological change was followed through the use of a Zeiss AXIO Observer A1 microscope.
The transition between normal epithelial cell biology and transformation into a malignant cell status can be defined histologically (Figure 2), as morphological changes developing hyperplasia, followed by dysplasia and a final diagnosis of carcinoma.
DU145 cells of 2 μmol/L tripterine acid treatment in typical apoptosis morphological changes are as follows: cytoplasmic density, chromosome condensation, marginalization, nuclear condensation, and formation of apoptotic bodies increased).
To better characterize the morphological changes and to follow the fine astrocytic processes that are not stained by GFAP, we co-injected a Mokola-pseudotyped lentiviral vector encoding green fluorescent protein (GFP) with the Mokola-pseudotyped vector encoding Htt171-82Q or 18Q.
Consistent with these morphological changes, differential gene expression followed by gene ontology analysis revealed that many genes (e.g., Myog, Mef2a, Mef2c, Ckm and Myh3) important for muscle development are downregulated in Huwe1 depleted myotubes.
