GGOH supplements reduced these morphological changes, demonstrating that ungeranylgeranylation of small G proteins contributed to the actions.
A low SMase activity already induced morphological and structural changes, demonstrating the potential of SMase to disturb erythrocyte homeostasis.
The animals were investigated at an age of ~18 months, well beyond the age when significant behavioral and morphological changes are demonstrated in this model (Nguyen et al. 2006; Cao et al. 2006; Kantor et al. 2006; Temel et al. 2006; Brooks et al. 2009; Faure et al. 2010; Miller et al. 2010; Hohn et al. 2011).
Cis-regulatory mutations have been shown to account for at least some instances of evolutionarily significant phenotypic change (Wray 2007), but trans-regulatory evolution can also affect adaptive morphological change, as demonstrated by the trans-mediation of flowering-time genes FRI and FLC in Arabidopsis allopolyploids (Wang et al. 2006).
Functional and morphological changes have been demonstrated in thyroid gland and adrenal cortex in many species exposed to organochlorinated compounds, including seals.
When switched from ITSFn to media for differentiation, A2B5+ cells demonstrated morphological changes after 3 or 4 days.
Various experiments have demonstrated morphological changes of dendritic spines that accompany synaptic plasticity, and these changes have been proposed to contribute to alterations in excitatory synaptic transmission during learning [9], [10], [11], [12], [13].
These cells also demonstrated morphological changes, transforming from spindle- to cobble stone-like in shape.
This prospective study of patients whose treatment for Hodgkin's disease in childhood included radiotherapy to the neck aimed to investigate the incidence and natural history of thyroid dysfunction and the morphological changes of the gland demonstrated on ultrasound.
Four herbal medicines, Tribulus terrestris, Glycyrrhiza spp., (alone and in combination with Paeonia lactiflora), Paeonia lactiflora (in combination with Cinnamomum cassia) and Cinnamomum cassia demonstrated morphological changes in polycystic ovaries and steroidogenesis, including reduced ovarian volume and cysts, lowered androgens, improved insulin sensitivity and increased oestradiol.
