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Scanning electron microscopy revealed morphological changes accompanied by the release of intracellular material from the fungal cells following exposure to Mul-1867.
At a threshold seeding density (104 cells/cm2), Y-27632 or selective ROCK-1 or ROCK-2 small interference RNA (siRNA) induced similar morphological changes accompanied by loss of alkaline phosphatase (AP) and Oct3/4 and expression of SOX-1, nestin and MAP2c but not markers of other lineages.
EMT is a complex multistage process that includes morphological changes accompanied by modulation of the expression of numerous proteins, in particular cytoskeletal and adhesion molecules [ 42].
In contrast, expression of activated MEK1 or MEK2 led to drastic morphological changes accompanied by loss of cell-cell contacts; the cells adopted a spindle-like fibroblast morphology, were more refractile and formed multilayers.
Furthermore, Wnt3a treatment significantly decreases the drug susceptibility of cholangiocarcinoma QBC939 cells to common chemotherapeutics [ 65], sensitizes malignant mesothelioma cells to cytotoxic drugs [ 58], and induces striking morphological changes accompanied by the rearrangement of the actin cytoskeleton in myeloma cells [ 66].
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Cells that undergo morphological changes accompanying CED-3 activation could recover completely when subjected to weak pro-apoptotic signals if they were not engulfed by phagocytic cells (Hoeppner et al., 2001; Reddien et al., 2001).
This study provides insights into the phase transformations and morphological changes accompanying the use of this type of ilmenite ore in a pressurized chemical looping combustion process, highlighting the need for proper adjustments to the design and operation of the process.
The morphological changes accompanying apoptosis have been described in detail above.
Answering this question demanded solving the technical challenges of 3D measurements and the large-scale morphological changes accompanying cellular differentiation.
The morphological changes accompanying the reprogramming of somatic cells to iPSCs can be visually identified by alkaline phosphatase staining.
Experiments in visual cortex examining morphological changes accompanying recovery from the effects of monocular deprivation induced by a reverse-suture paradigm reveal that axonal arbors from thalamic cells serving the formerly deprived eye show some corresponding increase in complexity and total length (Antonini et al. 1998).
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