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These morphological and immunophenotypical features were consistent with Burkitt's lymphoma, classified as stage III, Group B according to Murphy Stages.
In the other 15 cases, the presence of a normal karyotype together with the morphological and immunophenotypical characterisation was consistent with a diagnosis of non-neoplastic specimens.
Previous trials of PARP inhibitors showed significant effect in patients with BRCA1 germline mutation, but no such effect was noted in sporadic tumours even those showing morphological and immunophenotypical similarities to BRCA1-associated tumours (BRCA-ness) (Chen, 2011).
Further studies are needed to define the morphological and immunophenotypical changes within the prostate induced by chronic infection and to clarify a potential linkage between E. coli infection and inflammation in the aetiology of CaP.
Diagnosis of EN-NK/T-NT was made on the basis of combined morphological and immunophenotypical findings (including positive CD56 and cytotoxic proteins) as well as EBV positivity as determined by in situ hybridization (ISH) with an Epstein-Barr virus-encoded small RNA (EBER-1) probe, according to WHO classification [ 16].
Although, in this study, KPNA2 expression is in association with cytoplasmic localisation of BRCA1 and other key DDR such as RAD51, thereby leading to dysfunction of these nuclear proteins with morphological and immunophenotypical changes, which is similar to that seen in tumours featuring 'BRCA-ness' phenotype.
Similar(54)
The diagnosis of ALL was based on morphological, cytochemical, and immunophenotypical criteria.
In 12 patients the diagnosis of t-MDS or t-ANLL was confirmed by morphological, cytochemical and immunophenotypical analysis.
Tissue sections from formalin-fixed and paraffin-embedded tissue specimens were used for conventional histo-morphological evaluation and immunophenotypical analysis.
Clues to diagnosis were based on highly characteristic morphological, immunophenotypical and clinical features.
More recently, primary uveal lymphoma was suggested to be accurately subtyped as EMZL of MALT type (WHO lymphoma classification), since its morphological, immunophenotypical, and clinical features were identical to those of EMZL-MALT elsewhere [ 12].
More suggestions(15)
morphological and genetic
morphological and dynamic
morphological and molecular
morphological and electrophysiological
morphological and demographic
morphological and metabolic
morphological and componential
morphological and immunohistochemical
morphological and structural
morphological and microscopic
morphological and ultrastructural
morphological and biochemical
morphological and ecological
morphological and F-actin
morphological and hydrobiological
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