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During a productive infection, the prototype strain of parvovirus minute virus of mice (MVMp) induces dramatic morphological alterations to the fibroblast host cell A9, resulting in cell lysis and progeny virus release.
Next, we evaluated the morphological alterations to identify metacyclic forms in cultures.
The five selected derivatives produced significant morphological alterations to MDA-MB-231 cells after 72 h of treatment.
These assessments will enable an assessment of size and morphological alterations to global and regional areas of the brain.
We examined the morphological alterations to the optic vesicle in embryos that had been exposed to glucose in more detail by performing immunofluorescent staining for β-catenin.
LPS was administered via the intraperitoneal route (rather than orally) to exclude any mechanism that may involve morphological alterations to the apical side of the epithelial cells.
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In the current study, SEM observations confirmed different degrees of physical damage and morphological alteration to both Gram-positive bacteria and Gram-negative bacteria treated with δ-3-carene, α-asarone, pellitorine, or ciprofloxacin.
Cell cultures are prepared to initiate conjugation by starvation in very dilute buffer (typically 10 mM Tris), a treatment that also induces morphological alteration to a "fast swimmer" cell shape [ 55], changes in chromatin structure [ 56] and histone modification [ 57], and general and specific changes in mRNA abundance [ 14, 58].
Scanning electron microscopy observations showed different degrees of physical damage and morphological alteration to both Gram-positive and Gram-negative bacteria treated with α-asarone, δ-3-carene, pellitorine, or ciprofloxacin, indicating that they do not share a common mode of action.
Even a warm ischemia time of 6 hours leads to morphological alterations due to disintegration of the intestinal mucosal barriers, following the bacterial translocation and gangrene of the intestinal wall [ 2].
However, it is necessary to establish facial and cranial measurements in our population, in order to be able to define morphological alterations, and to adequately intervene for surgical correction [ 15].
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