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Morphological alterations like increase in membrane protrusions and disorganization of cell-cell contacts were observed by phase contrast microscopy in fascin-overexpressed cells.
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On the other hand, PEF elicited cardiomyogenic differentiation, which is commensurate with the tube-like morphological alterations along with the upregulation of cardiac specific markers.
Later, foetal acinar expression was frequently associated with evident morphological alterations in acini like dyskaryosis, enlarged cytoplasm or lumina.
Thus, oncogenic EMT could be defined as an EMT-like process in which carcinoma cells gain mesenchymal-like characteristics and/or lose epithelial characteristics; morphological alterations may or may not accompany such changes (see 'Breast cancer EMT mediators' section for further discussion).
These 'revertants' are most likely not predominantly those fibres that show morphological alterations, i.e. branching and splitting, as these generally showed 'mdx-like' dystrophin staining.
The intimate link between nucleolar structure and function is reflected by transcription-dependent changes in nucleolus-associated chromatin, overall morphological alterations in response to external cues, and the liquid droplet-like behavior of nucleolar compartments.
ALS-CSF has been shown to produce toxic effects on motor neuron cells like aberrant neurofilament phosphorylation and morphological alterations of nuclear and soma size.
The morphological alterations in TFM7-CS transgenic fruits prompted us to investigate whether SlCOBRA-like impacts genes encoding proteins involved in cell wall-degradation.
The up regulation of the EMT-specific genes is accompanied by morphological alterations consistent with a loosening of cell adhesion within the aggregates and adoption of a mesenchymal-like phenotype (data not shown).
Consistent with these morphological alterations, cells undergoing EMT show a change in the actin cytoskeleton from cortical F-actin type to stress fiber-like.
Nobody presented morphological alterations at brain CT examination.
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CEO of Professional Science Editing for Scientists @ prosciediting.com