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This morphological alteration was not apparent after single-agent treatment.
The nuclear morphological alteration was observed by staining cells with Hoechst33342.
The morphological alteration was observed in control and AgNPs treated HeLa cancer cells.
The most drastic morphological alteration was observed in the tpm1Δ mutant.
No morphological alteration was observed in the pulmonary tissue of mice exposed to 10 μmol/kg of (PhTe 2, for 7 or 14 days, when compared with the control group (data not shown).
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Differential mitochondrial membrane potential decrease, mitochondrial enzymatic dysfunction, and mitochondrial morphological alteration are exhibited in two cell lines.
Many assays for oncogenic transformation have been developed ranging from those in established rodent cell lines where morphological alteration is scored, to those in human cells growing in nude mice where tumor invasiveness is scored.
This morphological alteration is accompanied by an increase in the expression of the protein BNIP3 (Bcl2/adenovirus E1B 19 kDa interacting protein 3) as well as a decrease in the abundance of mitofusins 1 and 2, two proteins involved in mitochondrial fusion.
Alterations in protein secretion, intracellular signaling, and cell morphology were monitored; and the role of integrin signaling in MSeA-induced morphological alterations was investigated using divalent cation treatments.
Likewise, typical evolution of necrotic morphological alterations was observed when the light dose was increased to 3.6 J/cm.
Significant reduction in viability of protoscoleces was observed with all tested strains, the remarkable tegumental damage associated with distinct morphological alterations was also observed, 2(b), 2(c), 2(d), and 2 e)), as compared to the PBS control protoscoleces).
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