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Morphological abnormalities have been reported for the hippocampi and amygdalae in young schizophrenia patients, but very little is known about the pattern of abnormalities in elderly schizophrenia patients.
No gross morphological abnormalities have been observed in the hippocampus of Dyrk1A+/− mice, but detailed morphometric analysis needs to be performed to reveal whether defects in this structure, similar to those in the cortex, may associate Dyrk1A deficiency with hippocampal dysfunction.
Minor adrenal morphological abnormalities have been observed in patients with lung cancer.
Surgical techniques to address the underlying morphological abnormalities have evolved with the concept of FAI.
Minor adrenal morphological abnormalities have also been observed in patients with lung cancer.
In gall-forming aphids, severe morphological abnormalities have been documented from Fukushima samples, which are rare from other samples [ 8].
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Previous studies of monosomic mice for Mmu17 and Mmu10 syntenic regions corresponding to the telomeric part of Hsa21q have not revealed any morphological abnormalities and have shown only mild behavioural phenotypes (Besson et al., 2007; Duchon et al., 2011; Sahún et al., 2014; Yu et al., 2010).
Indeed, some of the above-mentioned morphological and functional abnormalities have also been described in uncomplicated alcoholism, suggesting graded effects of brain abnormalities [47].
On the other hand, no morphological or histological abnormalities have been reported in mice targeted with the disruption of DS epimerase-2 encoded by Dsel [ 93].
Fragile X syndrome (FXS) is characterized by core deficits in intellectual function, hyperarousal and anxiety, repetitive behaviors, and morphological abnormalities and has a known genetic cause.
Some studies have examined changes in a paediatric population [ 2]; however, the specific morphological abnormalities in children have not been well-defined.
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