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Patients with CD56+ blast cells were selected, and morphologic review was performed.
Bone marrow morphologic review may show increasing blasts or dysplastic features.
Initial evaluations typically involve a physical examination and morphologic review and immunotyping of the blood, bone marrow, and, where appropriate, a lymph node or spleen biopsy.
If the original hematoxylin and eosin sections were unavailable for review (3 cases), the morphologic review was performed by telepathology on scanned whole-slide sections.
The morphologic review of the renal tumor registry at the Department of Pathology, Charles University, Pilsen, Czech Republic, identified only 1 case from 2004 locally resected tumors, with an estimated incidence of 0.05%.
The 10% diagnostic discrepancy rate quoted above does emphasise the need for morphologic review of submitted tissues so that extremely necrotic or contaminated tissue aliquots ('normal' with tumour) are not served to investigators.
Similar(53)
Central morphologic reviews are performed on the formalin-fixed tissues sent via the dual-chamber kits which represent the mirror-image of samples of snap-frozen tumour and normal adjacent tissue also included in the kit.
ZEB1 as with ZEB2, Snail1 and 2, Twist1 and 2, TCF3 and 4, FoxC2, Goosecoid, KLF8 and Id1 orchestrate EMT transcriptional and morphologic changes (reviewed in [ 6]).
Review of magnetic resonance imaging (MRI) was undertaken by one radiologist, who was blinded to pathology review and morphologic group assignment.
Intensive cytogenetic, morphologic, and flow cytometry review [ 19], parental interviews [ 20, 21] and biologic and environmental sampling [ 22] were performed, as well as characterization of NRAS and KRAS mutations [ 23].
This study reviews the morphologic and radiographic features of 44 pediatric CN prospectively enrolled on a Children's Oncology Group protocol from 2007 to 2013.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com