The k values for inter- and intraobserver agreement for the gastroscopic mucosal morphologic patterns were significant.
In our study, the gastric mucosal morphologic patterns were classified into 5 morphologic patterns using C-NBI gastroscopy.
Type 1 gastric mucosal morphologic patterns were associated with regular arrangement of surface epithelium, with no infiltration by inflammatory cells.
Type 1 and type 2 gastric mucosal morphologic patterns were statistically significant in predicting Helicobacter pylori negative status as compared with other mucosal morphologic patterns (58/60, P < 0.01).
Type 3, type 4, or type 5 gastric mucosal morphologic patterns were statistically significant in predicting Helicobacter pylori positive status as compared with other mucosal morphologic patterns (132/140, P < 0.01).
Furthermore, the sensitivity, specificity, and positive and negative predictive values of type 3, type 4, or type 5 morphologic patterns for predicting the Helicobacter pylori positive gastric morphologic patterns were 94.28%, 96.66%, 98.50%, and 87.87%, respectively, with good correlation between gastric mucosal morphologic patterns and the severity of inflammation (P < 0.01).
A similar morphologic pattern was seen in the Q344terrho−/− retinas at p60 (Fig. 4, I K).
The observed gastric mucosal morphologic pattern was classified into 5 morphologic patterns: type 1: regular arrangement of collecting venules, type 2: cone-shaped gastric pits, type 3: rod-shaped gastric pits with prominent sulci, type 4: ground glass-like pattern, and type 5: dark brown patches.
When curve profiles and morphologic enhancement patterns were combined, sensitivity increased to 100%.
Thus gastric mucosal morphologic pattern may be useful for " site specific biopsy" of the areas with suspected Helicobacter pylori infection in daily practice.
