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Therefore, tissue microarrays were constructed from a series of pure DCISs, a large set of markers were used for IHC, and unsupervised hierarchical cluster analysis was performed to evaluate results; clustering was correlated with morphologic grade of DCIS as assessed on whole tumour slides.
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Irani, M. et al. Morphologic grading of euploid blastocysts influences implantation and ongoing pregnancy rates.
Analysis of Survivin protein expression in our study of paediatric ependymal and CP tumours showed that Survivin is expressed in all morphologic grades of these tumours.
In addition to evaluating different RCC subtypes, a study by Palmowski et al. reported that DCE pMRI can also be used to estimate the morphologic grading of RCC and hence assess adverse oncologic features.
Our study does support a potential use for the sc-10811 antibody in determining or helping to confirm the morphologic grades of ependymomas and choroidal tumours, as these particular brain tumours are notoriously difficult to grade on the basis of histology alone (Burger, 1994).
The results of these studies suggest that control subjects have a similar prevalence of morphologic abnormalities as those at risk for OA and those with mild/moderate OA; thus, the use of morphologic grading to discriminate between subjects with early OA and controls may be challenging.
In addition to size, it is possible that other poorly documented factors (e.g. local invasiveness, proliferation rate, or morphologic grade) also impact on the risk of local relapse, and are confounding factors in a dose-response analysis.
Morphologic grading was recorded as described previously (18).
Interobserver variation in gross morphologic grading was verified by measuring agreement with the κ statistic.
The disappearance of the keratin immunostaining in ballooned hepatocytes is reasonably specific for ASH and NASH, since it is not seen in ballooned cells of viral hepatitis or toxic damage and can therefore be used as an objective morphologic parameter in grading of steatohepatitis (Lackner et al. 2008).
Results: Alterations in levator ani morphologic features are not dependent on the grade of the prolapse, and not all women with pelvic floor prolapse have abnormal morphologic features.
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