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In addition, similar molecular and morphologic effects were true to a lesser extent for PCB-61.
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Partial recovery from EE2 exposure during early sexual differentiation can therefore occur with a sufficient period of depuration, but certain morphologic effects are long lived.
As demonstrated in our studies, the morphologic effects of PCBs are not as severe as those seen in response to strong estrogenic stimuli, such as high or moderate levels of DES, and are therefore difficult to assess.
Treatment effects are monitored by serial MRI, and two characteristic morphologic changes in the brain have been well documented [19], [20].
Although morphologic evolution due to channel incision has been documented and modeled by others, ecological effects, particularly water quality effects, are less well understood.
However, an improved correlation between in vivo activity and the minimum effective concentration (MEC) – the lowest dose of drug that causes morphologic effects on fungal hyphae – was observed [ 12].
However, the morphologic effects of low level DES exposure and Aroclor 1254 were not identical.
Analysis of the true and apparent electrocatalytic activities revealed the O2-evolution reaction rate is affected by oxide composition due to morphologic effects.
Apoptosis quantified by morphologic changes was induced in a dose-dependent manner and this effect was synergistic with Erlotinib (Fig. 1C).
Dental and dentoalveolar asymmetry, mandibular morphologic asymmetry, and condylar morphologic asymmetry were expressed as linear and angular measurements in millimeters and degrees, respectively (Table 2).
These morphologic findings were highly suspicious of a malignant tumour.
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