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Of note, however, are previous reports of pTDP43 labelling intraneuronal dot-like structures that show morphologic characters consistent with granulovacuolar degeneration (GVD) [ 19], as well as partially co-localising with pathological tau inclusions in Alzheimer's disease [ 20].
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Are the characters consistent?
In GGP4s, "pleomorphic cells" were less frequent compared to GGP2s and GGP3s, although we could not find definite morphologic characters.
The species were identified on the basis of morphologic characters and the mitochondrial cytochrome b (cytb) gene sequence.
Taxonomic classification of viruses is an evolving discipline that in early years was based primarily on morphologic characters.
Relations of compatibility concerning morphologic characters were given due consideration by Hennig [ 16] and a procedure for testing compatibility of phylogenetic hypotheses under the term "consistency" was developed by Wilson [ 17].
When information about ospC was included in the data set, it was included as a heavily weighted morphologic character in MrBayes, not as DNA sequence data.
Is the behavior of each character consistent with his/her character as developed over the years?
16 The rash was typically eczematous and maculopapular in character, consistent with a drug-induced eruption.
Phylogenetic analyses based on morphological characters have not yielded consistent results either, e.g. [ 9, 10].
MTUS1/ATIP3a knockdown in SACC-83 cells also induced morphologic changes consistent with EMT, with the cells displaying irregular fibroblast-like morphology (Additional file 9: Figure S5).
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