Sentence examples for morphologic changes typical from inspiring English sources

After knockdown of LC3B for 72 h, DLD-1 cells underwent morphologic changes typical of apoptosis, for example, chromatin condensation and a shrunken nucleus).

Both cell types exhibited the morphologic changes typical of osteogenic differentiation on day 7 in osteogenic medium, including nodule formation and the production of mineralised matrix.

Compared to untreated controls (left column) cytokine-treated cultures displayed cytoskeletal reorganization and morphologic changes, typical of reactive astrocytes (middle column), including a spherical cell body and multiple highly branched processes.

While some studies have implicated apoptosis as a major cell death mode in phenothiazine-treated cells, we found that the percentage of SCLC exhibiting nuclear morphologic changes typical of apoptosis, such as chromatin condensation and fragmentation, remained low (10%) even at the highest TFP concentrations, where >98% of all cells lost the ability to exclude propidium iodide (PI; data not shown).

Interestingly, Marchiando et al. observed that morphologic changes typical of apoptosis were not apparent until the nucleus of the shedding cell had moved above the nuclei of adjacent cells, suggesting that, in the order of events, shedding leads to apoptosis [ 44].

However, peptide-treated cells show the typical morphologic changes associated with apoptosis.

In this study, we found typical morphologic changes and a high percentage of TUNEL-positive cells in three pancreatic cancer cell lines after treatment using Bi-C595 in vitro.

These effects on protein expression are accompanied by morphologic changes (membrane blebbing, chromatin condensation) typical of apoptosis in ErbB2-transfected, but not vector control, cells.

The control cells showed a typical epithelial cuboidal shape with a cobblestone morphology; however, they exhibited profound morphologic changes after exposure to β2-M (25 μM) for 72 h, becoming elongated in shape, disassociating from neighboring cells and losing their cobblestone monolayer morphology.

Moreover, morphologic changes of the proximal femur make revision THA a demanding procedure.

K. Sugimoto et al. (2010a) have also detected and reported these morphologic changes.