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Herein, we present for the first time the morphologic and phenotypic outcome of one such patient.
Histology is an unreliable means of predicting clinical behavior, but this study has identified some morphologic and phenotypic features that may indicate a more aggressive lesion.
A large population of differentiated de-ATSC showed morphologic and phenotypic characteristics of astrocytes (GFAP), and neurons (MAP2ab and NF160 [approximately 45% of the total population]; Figure 6A).
We have previously generated an immortalized cell line of human microglia, HMO6, which carries morphologic and phenotypic expression characteristic of primary human microglia [18], [19].
The complexity of the wound environment has been recreated in human, bioengineered in vitro 3D tissues known as human skin equivalents (HSE), that have many morphologic and phenotypic properties of human skin.
It has been characterized in full for its morphologic and phenotypic features.
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Formalin-fixed and paraffin-embedded cell blocks were processed to obtain seriate tissue sections for both morphologic analysis and phenotypic studies.
The cells were then counted and used for phenotypic, morphologic, and functional analyses without further separation.
Immortalized PNMEC cultures are shown to retain key phenotypic, morphologic and biochemical properties highly characteristic of primary microvascular endoneurial endothelial cells.
Here, we report the stable immortalization of rat PNMEC cultures and demonstrate their retention of key phenotypic, morphologic and biochemical characteristics expected of MECs from the endoneurium of rat peripheral nerve.
Although enrichment of DCs in RA synovial tissue and fluid and in seronegative synovial fluid has been reported [ 20- 26], the considerable phenotypic, morphologic and functional variations between DC subsets related to lineage, stage of maturation and tissue localisation remains less well understood.
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